Adsense - Google’s powerful ad network which pays on click generated by your visitors. There are many high paying keywords which gives publishers up to $15 per click.
Bidvertiser – Publishers banned by Google Adsense can try bidvertiser which has good ad serving network and pays also good amount to their publishers.

Adbrite – Is also good publisher network which serve good advertisements and pays up to 5 cent per click. 
PayPopUp – is a CPM network which pays on pop up generated by your webpage and pays on 1000 visits. PayPopUp is good for high traffic sites and easy to earn $50 per day with good sites.

 

Infolinks – Contextual based advertising solution of publishers and advertisers. Infolinks place a java script on publishers site and contextual ads for advertisers are distribute. Publishers earn money when someone clicks on advertisers ad. 

Advertising365 – another CPM network which pays on pop up generated by visits. Publishers earn money on eCPM based on different countries traffic. Best option for high traffic site webmasters. 

Commission Junction: Why CJ? CJ is easy to get accepted and you can find almost every advertisers with CJ. Definitely you will have highest payout in the industry. Almost every affiliate join CJ, because it’s easy to make money. All you need is to apply different advertisers and you are ready to start marketing your advertisers offers to get paid per lead or sale. I haven’t seen any network like CJ. Guaranteed commission on-time, huge affiliate offers and excellent support with net 30 payment cycle via Checks and bank Wire.

 

LinkShare: Another well-know marketing agency specialized in pay per sale business. You can find top brand names here. There are huge advertisers with highest commission. You will get paid up to 15% per sale. Apply for your favorite advertiser individually and wait till they approve your application. They also have two-tier affiliate program and pay affiliate up to $1.50 per lead to refer new affiliates. Linkshare offers net 30 payout via Checks 

CPALead: very popular among the high traffic site webmaster. CPALead is easy to monetize high traffic site and helps publisher to make huge money by allowing them to place content blocking widget on their web-page. CPALead is the brand name in the affiliate industry and they have huge incentive offers as well as international offers. They love affiliates and they do pay monthly via Paypal only.

 

PepperJamNetwork : he Pepperjam Affiliate Network represents some of the biggest and hippest brands on the market today. The network is a pioneer in the way that it started out as an affiliate, and now is one of the biggest and most trusted affiliate agencies in the United States. Join this greatly experienced affiliate program and start earning money from your website. And oh… Did we mention that there’s a $10 Sign-On Bonus waiting for you that is a new affiliate 

ShareASale : The idea – and the implementation – are simple. You decide which merchants to promote and how to promote them, and when commissions are generated, you can see your stats in real-time. All payments are consolidated from the programs you participate in, and are paid with one check or direct deposit by ShareASale